Image Comics' East of West will end with issue #46 according to writer/co-creator Jonathan Hickman.
HEY!— Jonathan Hickman (@JHickman) August 15, 2018
East of West VOLUME 8 is out today. Only two volumes (~eight issues) left. So much shit going down.
This week's East of West. Vol. 8 includes issues #35 through #38.
Earlier this month the publisher removed East of West #39 from Diamond Comic Distributors' release schedule following a series of delays, but they plan to resolicit the issue in future months. The issue was the planned beginning of a new arc titled "These Brothers of Destiny."