In the final moments of Vertigo Comics' Comic-Con International: San Diego panel, newly-minted Executive Editor Mark Doyle and Group Editor Jamie S. Rich showed off this trailer they said will celebrate the imprint's 25-year anniversary in 2018. In addition to stills from earlier work, it also featured some new artwork - presumably from new projects.
Take a look:
Stanley "Artgerm" Lau has confirmed one of the pieces, an illustration of Death, is something he's done recently "for a special event." Three other illustrations - two Sandman drawings, and an Invisibles painting - are seemingly new and by Jim Lee, Jae Lee, and Jeff Lemire, respecitvely.
Here they are:
The video ends with a graphic with the numbers "080818" which could easily be translated to 08/08/18, or August 8, 2018 - a Wednesday.
Vertigo Comics officially launched in January 1993, so this wouldn't merely be the day-and-date 25th anniversary of the DC imprint.
While series revivals of each are possible, it seems more likely that the date will be the announcement - or release - of some kind of related project.