Concept artist Jeffrey Henderson has revealed never-before-seen concept art from Sam Raimi's cancelled Spider-Man 4, featuring early designs for both the Vulture and Mysterio. John Malkovich was reportedly in negotations to play the Vulture in this planned 2011 film, but the casting list for Mysterio was never substantiated. Take a look:
You can see more of Henderson's work on Spider-Man 4 at his website.
Spider-Man 4 was cancelled when Raimi couldn't agree to Sony's accelerated schedule to produce the film and two planned follow-ups back-to-back.